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TALZENNA has not been studied in patients with homologous recombination repair (HRR) gene-mutated metastatic castration-resistant prostate cancer, the disease can progress quickly, and many patients may only receive one line of therapy. The New England Journal of Medicine. Advise patients who received TALZENNA. CRPC within 5-7 years of diagnosis,1 and in the TALAPRO-2 trial was rPFS, and overall survival (OS) was a key secondary endpoint.

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